Your query retrieve from your table named TABLE all rows with the column replaced.
About UPDATE your database you must use UPDATE command in this way:
UPDATE table SET column = replace(replace(column,CHAR(13),''),CHAR(10),'')
If you want condition the UPDATE about the satisfaction of some conditions, so you must add the WHERE clause.
For example
UPDATE table SET column = replace(replace(column,CHAR(13),''),CHAR(10),'')
WHERE column_2 = 'XXX'