If you want 3D, WebGL is the only option. The good news is that WebGL is slated for inclusion in IE11.
If you want 2D, you have options:
- Canvas.
- SVG.
- HTML Elements.
Of these, for most gaming solutions, Canvas is the only sensible option.
But I recommend trying out some JS gaming libraries to deal with the core rendering code, rather than writing it yourself -- it'll save you a lot of time and effort. See here for a list of possible libraries you could try.