Maybe you could export your .xlsx to a .csv file?
Then you could try:
import csv
with open('file.csv','rb') as file:
contents = csv.reader(file)
[x for x in contents]
This may be useful: http://docs.python.org/2/library/csv.html#csv.reader
Hope that helps!
EDIT:
If you want to locate a spectific cell, such as F13, you could make a nested list like a matrix and them refer to each element:
import csv
with open('file.csv','rb') as file:
contents = csv.reader(file)
matrix = list()
for row in contents:
matrix.append(row)
And then access F13 with matrix[5][12]
.
P.S.: I did not test this. If "row" is a list with each cell as an element, you keep appending all lines to the matrix, so the first index is row number and the second is the column number.