This is untested code, but it's a general idea how it should have been written. If you clone the source on the original page you can adjust it for your own purposes (i.e. fix it):
require 'nokogiri'
doc = Nokogiri::XML(content)
tweets = doc.at('profile strong').text.delete('.,').to_i
following = doc.at('following strong').text.delete('.,').to_i
followers = doc.at('followers strong').text.delete('.,').to_i
The above three lines can be reduced to something like:
tweets, following, followers = %w[profile following followers].map{ |tag|
doc.at("#{ tag } strong").text.delete(',.').to_i
}
Again, without a usable sample of the XML/HTML I can't do much more, but as a practice we (programmers) shouldn't use regular expressions to try to parse XML or HTML. It's much to easy to break a pattern with either of those types of files.