ADE doesn't support MathML. If you are dependent on using ADE, your best bet is to use PNG graphics in your EPUB. This will enable your EPUB + Math to work on many more readers, since MathML is not well supported either inside or outside the browsers.
Some EPUB readers have incorporated the MathJax javascript library into their implementations. You can see which readers have MathJax support here: http://www.mathjax.org/resources/epub-readers/
Hope this helps.
Best regards, Jean K.