No, SecureString no. It's just a pointer to the actual protected memory address, tied up to the Windows DPAPI. Whatever you do will always require some kind of coding.
If your are using MS SQL, you can have the encryption tasks right there: Encrypting by passphrase, symmetric keys or asymmetric keys.
Take a look at: http://blog.sqlauthority.com/2009/04/28/sql-server-introduction-to-sql-server-encryption-and-symmetric-key-encryption-tutorial-with-script/
or you might want to take a look at this great book: http://www.apress.com/9781430224648