You should have no problem with running PB10 applications on Windows 8, appart perhaps not being not fully compliant with Win8 standards (concerning the placement of application data files, access rights on files, and so on mostly related to UAC file virtualization).
Neither you should have big problems with running the IDE, but maybe some minor issues (I think about an issue on the retrieval argument editor on PB11.5 that could also address PB10).