Once you have created the database, it should be possible to open it and add reference:
Sub CreateDB()
Dim acApp As Access.Application
Dim dppath As String
dbpath = "z:\docs\newmsmdb.mdb"
''http://msdn.microsoft.com/en-us/library/office/ff835033.aspx
CreateDatabase dbpath, dbLangGeneral, dbVersion40
''http://msdn.microsoft.com/en-us/library/office/aa140509(v=office.10).aspx
Set acApp = New Access.Application
With acApp
.OpenCurrentDatabase dbpath
acApp.References.AddFromFile _
"c:\program files\common files\system\ado\msado15.dll"
End With
End Sub