Try this code:
string script = "$find('" + OptionsTabs.ClientID + "').get_tabs()[2]._hide();";
ClientScriptManager cs = Page.ClientScript;
String csname1 = "TabScript";
Type cstype = this.GetType();
cs.RegisterStartupScript(cstype, csname1, script, true);
As an alternative, since you're using MS Ajax and it has page lifecycle for client-side as well you can try Load
event in JavaScript, add this to clinet-side code:
Sys.Application.add_load(appLoaded);
function appLoaded(sender, eventArgs) {
$find('<%=OptionsTabs.ClientID%>').get_tabs()[2]._hide();
}