After a long research I got the solution, not exact solution, but it can help.
The long running since column indicate the time from where its first request start. It does not mean the request time is to complete any single request for any user. So, here nothing to worry on this high number.
Edit: http://blogs.msdn.com/b/yunjin/archive/2005/08/25/456355.aspx
http://blogs.msdn.com/b/yunjin/archive/2005/08/29/457150.aspx
http://social.msdn.microsoft.com/Forums/en/vsdebug/thread/17f783cd-d5af-4146-ab46-be80e62da750
And for memory leak I would recommend to use WinDbg. WinDbg ref:
http://blogs.msdn.com/b/alejacma/archive/2009/06/30/sos-cheat-sheet-net-2-0-3-0-3-5.aspx
http://geekswithblogs.net/.NETonMyMind/archive/2006/03/14/72262.aspx