It may be of interest to readers of this thread that Gerry Sussman's scmutils system is being ported to Clojure.
This is a very advanced CAS, offering things like automatic differentiation, literal functions, etc, much in the style of Maple.
It is used at MIT for advanced programs on dynamics and differential geometry, and a fair bit of electrical engineering stuff. It is also the system used in Sussman&Wisdom's "sequel" (LOL) to SICP, SICM (Structure and Interpretation of Classical Mechanics).
Although originally a Scheme program, this is not a direct translation, but a ground-up rewrite to take advantage of the best features of Clojure. It's been named sicmutils, both in honour of the original and of the book
This superb effort is the work of Colin Smith and you can find it at https://github.com/littleredcomputer/sicmutils .
I believe that this could form the basis of an amazing Computer Algebra System for Clojure, competitive with anything else available. Although it is quite a huge beast, as you can imagine, and tons of stuff remains to be ported, the basics are pretty much there, the system will differentiate, and handle literals and literal functions pretty well. It is a work in progress. The system also uses the "generic" approach advocated by Sussman, whereby operations can be applied to functions, creating a great abstraction that simplifies notation no end.
Here's a taster:
> (def unity (+ (square sin) (square cos)))
> (unity 2.0) ==> 1.0
> (unity 'x) ==> 1 ;; yes we can deal with symbols
> (def zero (D unity)) ;; Let's differentiate
> (zero 2.0) ==> 0
SicmUtils introduces two new vector types “up” and “down” (called “structures”), they work pretty much as you would expect vectors to, but have some special mathematical (covariant, contravariant) properties, and also some programming properties, in that they are executable!
> (def fnvec (up sin cos tan)) => fnvec
> (fnvec 1) ==> (up 0.8414709848078965 0.5403023058681398 1.5574077246549023)
> ;; differentiated
> ((D fnvec) 1) ==> (up 0.5403023058681398 -0.8414709848078965 3.425518820814759)
> ;; derivative with symbolic argument
> ((D fnvec) 'θ) ==> (up (cos θ) (* -1 (sin θ)) (/ 1 (expt (cos θ) 2)))
Partial differentiation is fully supported
> (defn ff [x y] (* (expt x 3)(expt y 5)))
> ((D ff) 'x 'y) ==> (down (* 3 (expt x 2) (expt y 5)) (* 5 (expt x 3) (expt y 4)))
> ;; i.e. vector of results wrt to both variables
The system also supports TeX output, polynomial factorization, and a host of other goodies. Lots of stuff, however, that could be easily implemented has not been done purely out of lack of human resources. Graphic output and a "notepad/worksheet" interface (using Clojure's Gorilla) are also being worked on.
I hope this has gone some way towards whetting your appetite enough to visit the site and give it a whirl. You don't even need Clojure, you could run it off the provided jar file.
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PS. Incidentally, to answer the original questiin directly, yes, sicmutils does support symbolic structures: you can set up a matrix representation where the entries are formulae, e.g. a matrix of rotation, and then evaluate (multiply) it for a given coordinate. It's wonderfully flexible in that way.